منابع مشابه
Brain Lipids and Mental Disorders
Phospholipases A2 (PLA,, EC 3.1.1.4) represent a growing superfamily of enzymes that catalyse the hydrolysis of glycerophospholipids at the sn-2 position, to produce free fatty acids and 1-acyl lysophospholipids [ 1,2,3]. The major polyunsaturated fatty acid generated upon PLA2 activation is arachidonic acid which is the rate-limiting precursor of eicosanoid formation. The lysoglycerophospholip...
متن کاملLipids of normal brain.
Anderson, R. G., Arth, C. E., Folkers, K., Harris, S. A., Kaczka, E. A., Mozingo, R., Southwick, P. L. & Wolf, D. E. (1947). J. Amer. chem. Soc. 69, 2753. Angier, R. B., Boothe, J. H., Cosulich, D. B., Fahrenbach, M. J., Hultquist, M. E., Hutchings, B. L., Kuh, E., Mowat, J. H., Northey, E. H., Seager, D. K., Semb, J., Sickels, J. P., Smith, J. M., Stokstad, E. L. R., Subbarrow, Y. & Waller, C....
متن کاملNutrients, Microglia Aging, and Brain Aging.
As the life expectancy continues to increase, the cognitive decline associated with Alzheimer's disease (AD) becomes a big major issue in the world. After cellular activation upon systemic inflammation, microglia, the resident immune cells in the brain, start to release proinflammatory mediators to trigger neuroinflammation. We have found that chronic systemic inflammatory challenges induce dif...
متن کاملInsulin and brain aging
The world's population is living much longer than in the past. It is crucial to find as many pathological factors that deteriorate the health condition and well-being of elderly people as possible. Loss of activity and functions over time is typical for elderly people. Aging affects brain function, metabolism and structure in different ways, and these effects have multiple etiologies. Cognitive...
متن کاملBrain Connectivity and Aging
here is growing evidence that in the aging process both the neural and the vascular aspects of brain function are affected. On the neural side, aging is associated with damage to the myelin sheaths and reduction in the total number of nerve fibers, resulting in a reduction in structural connectivity [1]. But connections in the brain are not only structural (i.e. synapses, axons, etc.); equally ...
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ژورنال
عنوان ژورنال: Journal of Japan Oil Chemists' Society
سال: 1992
ISSN: 1884-2003
DOI: 10.5650/jos1956.41.757